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Transcriptome-based network analysis related to M2-like tumor-associated macrophage infiltration identified VARS1 as a potential target for improving melanoma immunotherapy efficacy

RATIONALE: The M2-like tumor-associated macrophages (TAMs) are independent prognostic factors in melanoma. METHODS: We performed weighted gene co-expression network analysis (WGCNA) to identify the module most correlated with M2-like TAMs. The Cancer Genome Atlas (TCGA) patients were classified into...

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Detalles Bibliográficos
Autores principales: Wu, Zhengquan, Lei, Ke, Li, Huaizhi, He, Jiali, Shi, Enxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615154/
https://www.ncbi.nlm.nih.gov/pubmed/36303162
http://dx.doi.org/10.1186/s12967-022-03686-z