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Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis

BACKGROUND: Intestinal barrier dysfunction, which is associated with reactive enteric glia cells (EGCs), is not only a result of early sepsis but also a cause of multiple organ dysfunction syndrome. Inhibition of platelet activation has been proposed as a potential treatment for septic patients beca...

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Detalles Bibliográficos
Autores principales: Cheng, Bo, Du, Mengyu, He, Shuxuan, Yang, Lan, Wang, Xi, Gao, Hui, Chang, Haiqing, Gao, Wei, Li, Yan, Wang, Qiang, Li, Yansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615156/
https://www.ncbi.nlm.nih.gov/pubmed/36303116
http://dx.doi.org/10.1186/s10020-022-00556-8