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Inhibition of platelet activation suppresses reactive enteric glia and mitigates intestinal barrier dysfunction during sepsis
BACKGROUND: Intestinal barrier dysfunction, which is associated with reactive enteric glia cells (EGCs), is not only a result of early sepsis but also a cause of multiple organ dysfunction syndrome. Inhibition of platelet activation has been proposed as a potential treatment for septic patients beca...
Autores principales: | Cheng, Bo, Du, Mengyu, He, Shuxuan, Yang, Lan, Wang, Xi, Gao, Hui, Chang, Haiqing, Gao, Wei, Li, Yan, Wang, Qiang, Li, Yansong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615156/ https://www.ncbi.nlm.nih.gov/pubmed/36303116 http://dx.doi.org/10.1186/s10020-022-00556-8 |
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