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Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

BACKGROUND: Bipolar Disorder (BD) is a complex mental disease characterized by recurrent episodes of mania and depression. Lithium (Li) represents the mainstay of BD pharmacotherapy, despite the narrow therapeutic index and the high variability in treatment response. However, although several studie...

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Detalles Bibliográficos
Autores principales: Cattane, Nadia, Courtin, Cindie, Mombelli, Elisa, Maj, Carlo, Mora, Cristina, Etain, Bruno, Bellivier, Frank, Marie-Claire, Cynthia, Cattaneo, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615157/
https://www.ncbi.nlm.nih.gov/pubmed/36303132
http://dx.doi.org/10.1186/s12888-022-04286-3