PRR34-AS1 promotes exosome secretion of VEGF and TGF-β via recruiting DDX3X to stabilize Rab27a mRNA in hepatocellular carcinoma

BACKGROUND: Exosomes are deemed to be an important tool of intercellular communicators in cancer cells. Our study investigated the role of PRR34 long non-coding RNA antisense RNA 1 (PRR34-AS1) in regulating exosome secretion in hepatocellular carcinoma (HCC) cells. METHODS: Quantitative real-time po...

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Detalles Bibliográficos
Autores principales: Zhang, Zhilei, Zhou, Ye, Jia, Yuming, Wang, Chao, Zhang, Meng, Xu, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615160/
https://www.ncbi.nlm.nih.gov/pubmed/36303180
http://dx.doi.org/10.1186/s12967-022-03628-9