MCM2 in human cancer: functions, mechanisms, and clinical significance

BACKGROUND: Aberrant DNA replication is the main source of genomic instability that leads to tumorigenesis and progression. MCM2, a core subunit of eukaryotic helicase, plays a vital role in DNA replication. The dysfunction of MCM2 results in the occurrence and progression of multiple cancers throug...

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Detalles Bibliográficos
Autores principales: Sun, Yaoqi, Cheng, Zhongping, Liu, Shupeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615236/
https://www.ncbi.nlm.nih.gov/pubmed/36303105
http://dx.doi.org/10.1186/s10020-022-00555-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615236/
https://www.ncbi.nlm.nih.gov/pubmed/36303105
http://dx.doi.org/10.1186/s10020-022-00555-9

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