Apicoplast ribosomal protein S10-V127M enhances artemisinin resistance of a Kelch13 transgenic Plasmodium falciparum

BACKGROUND: The resistance of Plasmodium falciparum to artemisinin-based (ART) drugs, the front-line drug family used in artemisinin-based combination therapy (ACT) for treatment of malaria, is of great concern. Mutations in the kelch13 (k13) gene (for example, those resulting in the Cys580Tyr [C580...

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Detalles Bibliográficos
Autores principales: Kampoun, Tanyaluck, Srichairatanakool, Somdet, Prommana, Parichat, Shaw, Philip J., Green, Judith L., Knuepfer, Ellen, Holder, Anthony A., Uthaipibull, Chairat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615251/
https://www.ncbi.nlm.nih.gov/pubmed/36303209
http://dx.doi.org/10.1186/s12936-022-04330-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615251/
https://www.ncbi.nlm.nih.gov/pubmed/36303209
http://dx.doi.org/10.1186/s12936-022-04330-3

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