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Apicoplast ribosomal protein S10-V127M enhances artemisinin resistance of a Kelch13 transgenic Plasmodium falciparum

BACKGROUND: The resistance of Plasmodium falciparum to artemisinin-based (ART) drugs, the front-line drug family used in artemisinin-based combination therapy (ACT) for treatment of malaria, is of great concern. Mutations in the kelch13 (k13) gene (for example, those resulting in the Cys580Tyr [C580...

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Detalles Bibliográficos
Autores principales:	Kampoun, Tanyaluck, Srichairatanakool, Somdet, Prommana, Parichat, Shaw, Philip J., Green, Judith L., Knuepfer, Ellen, Holder, Anthony A., Uthaipibull, Chairat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615251/ https://www.ncbi.nlm.nih.gov/pubmed/36303209 http://dx.doi.org/10.1186/s12936-022-04330-3

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