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Tim-3 downregulation by Toxoplasma gondii infection contributes to decidual dendritic cell dysfunction

BACKGROUND: Women in early pregnancy infected by Toxoplasma gondii may have severe adverse pregnancy outcomes, such as spontaneous abortion and fetal malformation. The inhibitory molecule T cell immunoglobulin and mucin domain 3 (Tim-3) is highly expressed on decidual dendritic cells (dDCs) and play...

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Detalles Bibliográficos
Autores principales: Xie, Hongbing, Li, Zhidan, Zheng, Guangmei, Yang, Chunyan, Liu, Xianbing, Xu, Xiaoyan, Ren, Yushan, Wang, Chao, Hu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615254/
https://www.ncbi.nlm.nih.gov/pubmed/36303229
http://dx.doi.org/10.1186/s13071-022-05506-1