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Targeting myeloid suppressive cells revives cytotoxic anti-tumor responses in pancreatic cancer

Immunotherapy for cancer that aims to promote T cell anti-tumor activity has changed current clinical practice, where some previously lethal cancers have now become treatable. However, clinical trials with low response rates have been disappointing for pancreatic ductal adenocarcinoma (PDAC). One su...

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Detalles Bibliográficos
Autores principales: Sarhan, Dhifaf, Eisinger, Silke, He, Fei, Bergsland, Maria, Pelicano, Catarina, Driescher, Caroline, Westberg, Kajsa, Benitez, Itziar Ibarlucea, Humoud, Rawan, Palano, Giorgia, Li, Shuijie, Carannante, Valentina, Muhr, Jonas, Önfelt, Björn, Schlisio, Susanne, Ravetch, Jeffrey V., Heuchel, Rainer, Löhr, Matthias J., Karlsson, Mikael C.I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615326/
https://www.ncbi.nlm.nih.gov/pubmed/36310582
http://dx.doi.org/10.1016/j.isci.2022.105317