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Polygenic association of glomerular filtration rate decline in world trade center responders

BACKGROUND: The factors associated with estimated glomerular filtrate rate (eGFR) decline in low risk adults remain relatively unknown. We hypothesized that a polygenic risk score (PRS) will be associated with eGFR decline. METHODS: We analyzed genetic data from 1,601 adult participants with Europea...

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Detalles Bibliográficos
Autores principales: Koraishy, Farrukh M., Mann, Frank D., Waszczuk, Monika A., Kuan, Pei-Fen, Jonas, Katherine, Yang, Xiaohua, Docherty, Anna, Shabalin, Andrey, Clouston, Sean, Kotov, Roman, Luft, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615399/
https://www.ncbi.nlm.nih.gov/pubmed/36307804
http://dx.doi.org/10.1186/s12882-022-02967-5