Statins Inhibit Inflammatory Cytokine Production by Macrophages and Acinar-to-Ductal Metaplasia of Pancreatic Cells

BACKGROUND AND AIMS: Animal data show that the presence of an oncogenic Kras mutation in pancreatic acinar cells leads to acinar-to-ductal metaplasia (ADM), pancreatic intraepithelial neoplasia (PanIN), and pancreatic ductal adenocarcinoma (PDAC). Inflammatory macrophages play an important role in t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ako, Soichiro, Teper, Yaroslav, Ye, Linda, Sinnett-Smith, James, Hines, Oscar J., Rozengurt, Enrique, Eibl, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615480/
https://www.ncbi.nlm.nih.gov/pubmed/36313271
http://dx.doi.org/10.1016/j.gastha.2022.04.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615480/
https://www.ncbi.nlm.nih.gov/pubmed/36313271
http://dx.doi.org/10.1016/j.gastha.2022.04.012

Ejemplares similares