miR-31 from Mesenchymal Stem Cell-Derived Extracellular Vesicles Alleviates Intervertebral Disc Degeneration by Inhibiting NFAT5 and Upregulating the Wnt/β-Catenin Pathway

In this study, we explored the regulatory mechanism of intervertebral disc degeneration (IDD) that involves miR-31 shuttled by bone marrow mesenchymal stem cell-derived extracellular vesicles (BMSC-EVs) and its downstream signaling molecules. Nucleus pulposus cells (NPCs) were isolated and treated w...

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Detalles Bibliográficos
Autores principales: Wang, Baodong, Xu, Na, Cao, Li, Yu, Xiaojun, Wang, Shanxi, Liu, Qikun, Wang, Yinguang, Xu, Haoran, Cao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615555/
https://www.ncbi.nlm.nih.gov/pubmed/36311041
http://dx.doi.org/10.1155/2022/2164057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615555/
https://www.ncbi.nlm.nih.gov/pubmed/36311041
http://dx.doi.org/10.1155/2022/2164057

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