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Low-Dose Augmentation With Buprenorphine for Treatment-Resistant Depression: A Multisite Randomized Controlled Trial With Multimodal Assessment of Target Engagement

BACKGROUND: The experimental therapeutics approach that combines a placebo-controlled clinical trial with translational neuroscience methods can provide a better understanding of both the clinical and physiological effects of pharmacotherapy. We aimed to test the efficacy and tolerability of low-dos...

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Detalles Bibliográficos
Autores principales: Lee, Hyewon H., Blumberger, Daniel M., Lenze, Eric J., Anderson, Stewart J., Barch, Deanna M., Black, Kevin J., Cristancho, Pilar, Daskalakis, Zafiris J., Eisenstein, Sarah A., Huang, Yiyun, Li, Songye, Lissemore, Jennifer, McConathy, Jonathan, Mulsant, Benoit H., Rajji, Tarek K., Reynolds, Charles F., Su, Yi, Tu, Zhude, Voineskos, Daphne, Karp, Jordan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616305/
https://www.ncbi.nlm.nih.gov/pubmed/36325158
http://dx.doi.org/10.1016/j.bpsgos.2021.09.003