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Dabigatran reduces thrombin-induced neuroinflammation and AD markers in vitro: Therapeutic relevance for Alzheimer's disease

BACKGROUND: Vascular risk factors such as atherosclerosis, diabetes, and elevated homocysteine levels are strongly correlated with onset of Alzheimer's disease (AD). Emerging evidence indicates that blood coagulation protein thrombin is associated with vascular and non-vascular risk factors of...

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Detalles Bibliográficos
Autores principales: Bihaqi, Syed Waseem, Rao, Haripriya Vittal, Sen, Abhik, Grammas, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616330/
https://www.ncbi.nlm.nih.gov/pubmed/36324711
http://dx.doi.org/10.1016/j.cccb.2021.100014