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Dabigatran reduces thrombin-induced neuroinflammation and AD markers in vitro: Therapeutic relevance for Alzheimer's disease
BACKGROUND: Vascular risk factors such as atherosclerosis, diabetes, and elevated homocysteine levels are strongly correlated with onset of Alzheimer's disease (AD). Emerging evidence indicates that blood coagulation protein thrombin is associated with vascular and non-vascular risk factors of...
Autores principales: | Bihaqi, Syed Waseem, Rao, Haripriya Vittal, Sen, Abhik, Grammas, Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616330/ https://www.ncbi.nlm.nih.gov/pubmed/36324711 http://dx.doi.org/10.1016/j.cccb.2021.100014 |
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