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MicroRNA Regulates Early-Life Stress–Induced Depressive Behavior via Serotonin Signaling in a Sex-Dependent Manner in the Prefrontal Cortex of Rats

BACKGROUND: The underlying neurobiology of early-life stress (ELS)-induced major depressive disorder is not clearly understood. METHODS: In this study, we used maternal separation (MS) as a rodent model of ELS and tested whether microRNAs (miRNAs) target serotonin genes to regulate ELS-induced depre...

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Detalles Bibliográficos
Autores principales: McKibben, Lauren Allen, Dwivedi, Yogesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616342/
https://www.ncbi.nlm.nih.gov/pubmed/36325302
http://dx.doi.org/10.1016/j.bpsgos.2021.05.009