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MicroRNA Regulates Early-Life Stress–Induced Depressive Behavior via Serotonin Signaling in a Sex-Dependent Manner in the Prefrontal Cortex of Rats
BACKGROUND: The underlying neurobiology of early-life stress (ELS)-induced major depressive disorder is not clearly understood. METHODS: In this study, we used maternal separation (MS) as a rodent model of ELS and tested whether microRNAs (miRNAs) target serotonin genes to regulate ELS-induced depre...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616342/ https://www.ncbi.nlm.nih.gov/pubmed/36325302 http://dx.doi.org/10.1016/j.bpsgos.2021.05.009 |