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Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection

Measles is the most contagious airborne viral infection and the leading cause of child death among vaccine-preventable diseases. We show here that aerosolized lipopeptide fusion inhibitor, derived from heptad-repeat regions of the measles virus (MeV) fusion protein, blocks respiratory MeV infection...

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Detalles Bibliográficos
Autores principales: Reynard, Olivier, Gonzalez, Claudia, Dumont, Claire, Iampietro, Mathieu, Ferren, Marion, Le Guellec, Sandrine, Laurie, Lajoie, Mathieu, Cyrille, Carpentier, Gabrielle, Roseau, Georges, Bovier, Francesca T., Zhu, Yun, Le Pennec, Deborah, Montharu, Jérome, Addetia, Amin, Greninger, Alexander L., Alabi, Christopher A., Brisebard, Elise, Moscona, Anne, Vecellio, Laurent, Porotto, Matteo, Horvat, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616412/
https://www.ncbi.nlm.nih.gov/pubmed/36307480
http://dx.doi.org/10.1038/s41467-022-33832-6