ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus

B cells orchestrate autoimmune responses in patients with systemic lupus erythematosus (SLE), but broad-based B cell–directed therapies show only modest efficacy while blunting humoral immune responses to vaccines and inducing immunosuppression. Development of more effective therapies targeting path...

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Detalles Bibliográficos
Autores principales: Manolakou, Theodora, Nikolopoulos, Dionysis, Gkikas, Dimitrios, Filia, Anastasia, Samiotaki, Martina, Stamatakis, George, Fanouriakis, Antonis, Politis, Panagiotis, Banos, Aggelos, Alissafi, Themis, Verginis, Panayotis, Boumpas, Dimitrios T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616496/
https://www.ncbi.nlm.nih.gov/pubmed/36306362
http://dx.doi.org/10.1126/sciadv.abo5840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616496/
https://www.ncbi.nlm.nih.gov/pubmed/36306362
http://dx.doi.org/10.1126/sciadv.abo5840

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