A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819

Mammalian genomes are a battleground for genetic conflict between repetitive elements and KRAB-zinc finger proteins (KZFPs). We asked whether KZFPs can regulate cell fate by using ZFP819, which targets a satellite DNA array, ZP3AR. ZP3AR coats megabase regions of chromosome 7 encompassing genes enco...

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Detalles Bibliográficos
Autores principales: Fernandes, Liane P., Enriquez-Gasca, Rocio, Gould, Poppy A., Holt, James H., Conde, Lucia, Ecco, Gabriela, Herrero, Javier, Gifford, Robert, Trono, Didier, Kassiotis, George, Rowe, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616502/
https://www.ncbi.nlm.nih.gov/pubmed/36306355
http://dx.doi.org/10.1126/sciadv.abp8085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616502/
https://www.ncbi.nlm.nih.gov/pubmed/36306355
http://dx.doi.org/10.1126/sciadv.abp8085

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