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A Polynesian-specific copy number variant encompassing the MICA gene associates with gout

Gout is of particularly high prevalence in the Māori and Pacific (Polynesian) populations of Aotearoa New Zealand (NZ). Here, we investigated the contribution of common population-specific copy number variation (CNV) to gout in the Aotearoa NZ Polynesian population. Microarray-generated genome-wide...

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Detalles Bibliográficos
Autores principales: Wang, Ke, Cadzow, Murray, Bixley, Matt, Leask, Megan P, Merriman, Marilyn E, Yang, Qiangzhen, Li, Zhiqiang, Takei, Riku, Phipps-Green, Amanda, Major, Tanya J, Topless, Ruth, Dalbeth, Nicola, King, Frances, Murphy, Rinki, Stamp, Lisa K, de Zoysa, Janak, Wang, Zhuo, Shi, Yongyong, Merriman, Tony R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616569/
https://www.ncbi.nlm.nih.gov/pubmed/35451026
http://dx.doi.org/10.1093/hmg/ddac094