Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways

Parkinson’s disease (PD) is a neurological disorder with complex interindividual etiology that is becoming increasingly prevalent worldwide. Elevated alpha-synuclein levels can increase risk of PD and may influence epigenetic regulation of PD pathways. Here, we report genome-wide DNA methylation and...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaffner, Samantha L, Wassouf, Zinah, Lazaro, Diana F, Xylaki, Mary, Gladish, Nicole, Lin, David T S, MacIsaac, Julia, Ramadori, Katia, Hentrich, Thomas, Schulze-Hentrich, Julia M, Outeiro, Tiago F, Kobor, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616577/
https://www.ncbi.nlm.nih.gov/pubmed/35567546
http://dx.doi.org/10.1093/hmg/ddac104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616577/
https://www.ncbi.nlm.nih.gov/pubmed/35567546
http://dx.doi.org/10.1093/hmg/ddac104

Ejemplares similares