Efficient secretory production of proline/alanine/serine (PAS) biopolymers in Corynebacterium glutamicum yielding a monodisperse biological alternative to polyethylene glycol (PEG)

BACKGROUND: PAS biopolymers are recombinant polypeptides comprising the small uncharged l-amino acids Pro, Ala and/or Ser which resemble the widely used poly-ethylene glycol (PEG) in terms of pronounced hydrophilicity. Likewise, their random chain behaviour in physiological solution results in a str...

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Detalles Bibliográficos
Autores principales: Friedrich, L., Kikuchi, Y., Matsuda, Y., Binder, U., Skerra, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616612/
https://www.ncbi.nlm.nih.gov/pubmed/36307781
http://dx.doi.org/10.1186/s12934-022-01948-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616612/
https://www.ncbi.nlm.nih.gov/pubmed/36307781
http://dx.doi.org/10.1186/s12934-022-01948-5

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