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Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging

The kynurenine pathway is implicated in aging, longevity, and immune regulation, but longitudinal studies and assessment of the cerebrospinal fluid (CSF) are lacking. We investigated tryptophan (Trp) and downstream kynurenine metabolites and their associations with age and change over time in four c...

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Detalles Bibliográficos
Autores principales: Solvang, Stein-Erik H., Hodge, Allison, Watne, Leiv Otto, Cabral-Marques, Otavio, Nordrehaug, Jan Erik, Giles, Graham G., Dugué, Pierre-Antoine, Nygård, Ottar, Ueland, Per Magne, McCann, Adrian, Idland, Ane-Victoria, Midttun, Øivind, Ulvik, Arve, Halaas, Nathalie B., Tell, Grethe S., Giil, Lasse M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616658/
https://www.ncbi.nlm.nih.gov/pubmed/36312896
http://dx.doi.org/10.1155/2022/5019752