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Human amniotic epithelial cells exert anti-cancer effects through secretion of immunomodulatory small extracellular vesicles (sEV)

We identified here mechanism by which hAECs exert their anti-cancer effects. We showed that vaccination with live hAEC conferred effective protection against murine colon cancer and melanoma but not against breast cancer in an orthotopic cancer cell inoculation model. hAEC induced strong cross-react...

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Detalles Bibliográficos
Autores principales: Bolouri, Mohammad-Reza, Ghods, Roya, Zarnani, Kayhan, Vafaei, Sedigheh, Falak, Reza, Zarnani, Amir-Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616706/
https://www.ncbi.nlm.nih.gov/pubmed/36307848
http://dx.doi.org/10.1186/s12935-022-02755-z