Cargando…

Establishment of centromere identity is dependent on nuclear spatial organization

The establishment of centromere-specific CENP-A chromatin is influenced by epigenetic and genetic processes. Central domain sequences from fission yeast centromeres are preferred substrates for CENP-A(Cnp1) incorporation, but their use is context dependent, requiring adjacent heterochromatin. CENP-A...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Weifang, McHugh, Toni, Kelly, David A., Pidoux, Alison L., Allshire, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616734/
https://www.ncbi.nlm.nih.gov/pubmed/35830853
http://dx.doi.org/10.1016/j.cub.2022.06.048