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Structure and function of the N-terminal extension of the formin INF2

In INF2—a formin linked to inherited renal and neurological disease in humans—the DID is preceded by a short N-terminal extension of unknown structure and function. INF2 activation is achieved by Ca(2+)-dependent association of calmodulin (CaM). Here, we show that the N-terminal extension of INF2 is...

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Detalles Bibliográficos
Autores principales: Labat-de-Hoz, Leticia, Comas, Laura, Rubio-Ramos, Armando, Casares-Arias, Javier, Fernández-Martín, Laura, Pantoja-Uceda, David, Martín, M. Teresa, Kremer, Leonor, Jiménez, M. Angeles, Correas, Isabel, Alonso, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616786/
https://www.ncbi.nlm.nih.gov/pubmed/36306014
http://dx.doi.org/10.1007/s00018-022-04581-y