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Structure and function of the N-terminal extension of the formin INF2
In INF2—a formin linked to inherited renal and neurological disease in humans—the DID is preceded by a short N-terminal extension of unknown structure and function. INF2 activation is achieved by Ca(2+)-dependent association of calmodulin (CaM). Here, we show that the N-terminal extension of INF2 is...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616786/ https://www.ncbi.nlm.nih.gov/pubmed/36306014 http://dx.doi.org/10.1007/s00018-022-04581-y |