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Mitotic kinase oscillation governs the latching of cell cycle switches

In 1996, Kim Nasmyth(1) proposed that the eukaryotic cell cycle is an alternating sequence of transitions from G(1) to S-G(2)-M and back again. These two phases correlate to high activity of cyclin-dependent kinases (CDKs) that trigger S-G(2)-M events and CDK antagonists that stabilize G(1) phase. W...

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Detalles Bibliográficos
Autores principales: Novak, Bela, Tyson, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616797/
https://www.ncbi.nlm.nih.gov/pubmed/35504285
http://dx.doi.org/10.1016/j.cub.2022.04.016