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Affinity microfluidics enables high-throughput protein degradation analysis in cell-free extracts

Protein degradation mediated by the ubiquitin-proteasome pathway regulates signaling events in many physiological and pathological conditions. In vitro degradation assays have been instrumental in the understanding of how cell proliferation and other fundamental cellular processes are regulated. The...

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Detalles Bibliográficos
Autores principales: Brio, Lev, Wasserman, Danit, Michaely-Barbiro, Efrat, Barazany-Gal, Gal, Gerber, Doron, Tzur, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616816/
https://www.ncbi.nlm.nih.gov/pubmed/36307570
http://dx.doi.org/10.1038/s42003-022-04103-3