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Dearomatization of aromatic asmic isocyanides to complex cyclohexadienes

A dearomatization-dislocation-coupling cascade rapidly transforms aromatic isocyanides into highly functionalized cyclohexadienes. The facile cascade installs an exceptional degree of molecular complexity: three carbon-carbon bonds, two quaternary stereocenters, and three orthogonal functionalities,...

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Detalles Bibliográficos
Autores principales: Altundas, Bilal, Alwedi, Embarek, Song, Zhihui, Gogoi, Achyut Ranjan, Dykstra, Ryan, Gutierrez, Osvaldo, Fleming, Fraser F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616822/
https://www.ncbi.nlm.nih.gov/pubmed/36307409
http://dx.doi.org/10.1038/s41467-022-33807-7