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Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression
Blood-retinal barrier (BRB) dysfunction has been recognized as an early pathological feature in common eye diseases that cause blindness. The breakdown of endothelial cell-to-cell junctions is the main reason for BRB dysfunction, yet our understanding of junctional modulation remains limited. Here,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616849/ https://www.ncbi.nlm.nih.gov/pubmed/36307391 http://dx.doi.org/10.1038/s41420-022-01222-y |