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Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression

Blood-retinal barrier (BRB) dysfunction has been recognized as an early pathological feature in common eye diseases that cause blindness. The breakdown of endothelial cell-to-cell junctions is the main reason for BRB dysfunction, yet our understanding of junctional modulation remains limited. Here,...

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Detalles Bibliográficos
Autores principales: Zhao, Bowen, Ni, Yueqi, Zhang, Hong, Zhao, Yin, Li, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616849/
https://www.ncbi.nlm.nih.gov/pubmed/36307391
http://dx.doi.org/10.1038/s41420-022-01222-y