Structural mechanism of SGLT1 inhibitors

Sodium glucose co-transporters (SGLT) harness the electrochemical gradient of sodium to drive the uphill transport of glucose across the plasma membrane. Human SGLT1 (hSGLT1) plays a key role in sugar uptake from food and its inhibitors show promise in the treatment of several diseases. However, the...

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Detalles Bibliográficos
Autores principales: Niu, Yange, Cui, Wenhao, Liu, Rui, Wang, Sanshan, Ke, Han, Lei, Xiaoguang, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616851/
https://www.ncbi.nlm.nih.gov/pubmed/36307403
http://dx.doi.org/10.1038/s41467-022-33421-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616851/
https://www.ncbi.nlm.nih.gov/pubmed/36307403
http://dx.doi.org/10.1038/s41467-022-33421-7

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