TNF overexpression and dexamethasone treatment impair chondrogenesis and bone growth in an additive manner

Children with chronic inflammation are often treated with glucocorticoids (GCs) and many of them experience growth retardation. It is poorly understood how GCs interact with inflammatory cytokines causing growth failure as earlier experimental studies have been performed in healthy animals. To addre...

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Detalles Bibliográficos
Autores principales: Zhao, Yunhan, Celvin, Bettina, Denis, Maria C., Karagianni, Niki, Aulin, Cecilia, Zaman, Farasat, Sävendahl, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616891/
https://www.ncbi.nlm.nih.gov/pubmed/36307458
http://dx.doi.org/10.1038/s41598-022-22734-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616891/
https://www.ncbi.nlm.nih.gov/pubmed/36307458
http://dx.doi.org/10.1038/s41598-022-22734-8

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