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TNF overexpression and dexamethasone treatment impair chondrogenesis and bone growth in an additive manner
Children with chronic inflammation are often treated with glucocorticoids (GCs) and many of them experience growth retardation. It is poorly understood how GCs interact with inflammatory cytokines causing growth failure as earlier experimental studies have been performed in healthy animals. To addre...
Autores principales: | Zhao, Yunhan, Celvin, Bettina, Denis, Maria C., Karagianni, Niki, Aulin, Cecilia, Zaman, Farasat, Sävendahl, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616891/ https://www.ncbi.nlm.nih.gov/pubmed/36307458 http://dx.doi.org/10.1038/s41598-022-22734-8 |
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