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ESRP1-regulated isoform switching of LRRFIP2 determines metastasis of gastric cancer

Although accumulating evidence indicates that alternative splicing is aberrantly altered in many cancers, the functional mechanism remains to be elucidated. Here, we show that epithelial and mesenchymal isoform switches of leucine-rich repeat Fli-I-interacting protein 2 (LRRFIP2) regulated by epithe...

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Detalles Bibliográficos
Autores principales: Lee, Jihee, Pang, Kyoungwha, Kim, Junil, Hong, Eunji, Lee, Jeeyun, Cho, Hee Jin, Park, Jinah, Son, Minjung, Park, Sihyun, Lee, Minjung, Ooshima, Akira, Park, Kyung-Soon, Yang, Han-Kwang, Yang, Kyung-Min, Kim, Seong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616898/
https://www.ncbi.nlm.nih.gov/pubmed/36307405
http://dx.doi.org/10.1038/s41467-022-33786-9