Neurexin1α knockout rats display oscillatory abnormalities and sensory processing deficits back-translating key endophenotypes of psychiatric disorders

Neurexins are presynaptic transmembrane proteins crucial for synapse development and organization. Deletion and missense mutations in all three Neurexin genes have been identified in psychiatric disorders, with mutations in the NRXN1 gene most strongly linked to schizophrenia (SZ) and autism spectru...

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Detalles Bibliográficos
Autores principales: Janz, Philipp, Bainier, Marie, Marashli, Samuel, Schoenenberger, Philipp, Valencia, Miguel, Redondo, Roger L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616904/
https://www.ncbi.nlm.nih.gov/pubmed/36307390
http://dx.doi.org/10.1038/s41398-022-02224-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616904/
https://www.ncbi.nlm.nih.gov/pubmed/36307390
http://dx.doi.org/10.1038/s41398-022-02224-1

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