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Mitochondrial ROS signalling requires uninterrupted electron flow and is lost during ageing in flies

Mitochondrial reactive oxygen species (mtROS) are cellular messengers essential for cellular homeostasis. In response to stress, reverse electron transport (RET) through respiratory complex I generates high levels of mtROS. Suppression of ROS production via RET (ROS-RET) reduces survival under stres...

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Detalles Bibliográficos
Autores principales: Graham, Charlotte, Stefanatos, Rhoda, Yek, Angeline E. H., Spriggs, Ruth V., Loh, Samantha H. Y., Uribe, Alejandro Huerta, Zhang, Tong, Martins, L. Miguel, Maddocks, Oliver D. K., Scialo, Filippo, Sanz, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616974/
https://www.ncbi.nlm.nih.gov/pubmed/35355221
http://dx.doi.org/10.1007/s11357-022-00555-x