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Mitochondrial ROS signalling requires uninterrupted electron flow and is lost during ageing in flies
Mitochondrial reactive oxygen species (mtROS) are cellular messengers essential for cellular homeostasis. In response to stress, reverse electron transport (RET) through respiratory complex I generates high levels of mtROS. Suppression of ROS production via RET (ROS-RET) reduces survival under stres...
Autores principales: | Graham, Charlotte, Stefanatos, Rhoda, Yek, Angeline E. H., Spriggs, Ruth V., Loh, Samantha H. Y., Uribe, Alejandro Huerta, Zhang, Tong, Martins, L. Miguel, Maddocks, Oliver D. K., Scialo, Filippo, Sanz, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616974/ https://www.ncbi.nlm.nih.gov/pubmed/35355221 http://dx.doi.org/10.1007/s11357-022-00555-x |
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