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Evidence that conserved essential genes are enriched for pro-longevity factors

At the cellular level, many aspects of aging are conserved across species. This has been demonstrated by numerous studies in simple model organisms like Saccharomyces cerevisiae, Caenorhabdits elegans, and Drosophila melanogaster. Because most genetic screens examine loss of function mutations or de...

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Detalles Bibliográficos
Autores principales: Oz, Naci, Vayndorf, Elena M., Tsuchiya, Mitsuhiro, McLean, Samantha, Turcios-Hernandez, Lesly, Pitt, Jason N., Blue, Benjamin W., Muir, Michael, Kiflezghi, Michael G., Tyshkovskiy, Alexander, Mendenhall, Alexander, Kaeberlein, Matt, Kaya, Alaattin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616985/
https://www.ncbi.nlm.nih.gov/pubmed/35695982
http://dx.doi.org/10.1007/s11357-022-00604-5