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CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice

Cytochrome b(5) reductase 3 (CYB5R3) overexpression activates respiratory metabolism and exerts prolongevity effects in transgenic mice, mimicking some of the salutary effects of calorie restriction. The aim of our study was to understand how CYB5R3 overexpression targets key pathways that modulate...

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Detalles Bibliográficos
Autores principales: López-Bellón, Sara, Rodríguez-López, Sandra, González-Reyes, José A., Burón, M. Isabel, de Cabo, Rafael, Villalba, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616997/
https://www.ncbi.nlm.nih.gov/pubmed/35527283
http://dx.doi.org/10.1007/s11357-022-00574-8