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LncRNA-ZFAS1 Promotes Myocardial Ischemia-Reperfusion Injury Through DNA Methylation-Mediated Notch1 Down-Regulation in Mice

The most devastating and catastrophic deterioration of myocardial ischemia-reperfusion injury (MIRI) is cardiomyocyte death. Here we aimed to evaluate the role of lncRNA-ZFAS1 in MIRI and delineate its mechanism of action. The level of lncRNA-ZFAS1 was elevated in MIRI hearts, and artificial knockdo...

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Detalles Bibliográficos
Autores principales: Li, Mengmeng, Jiao, Lei, Shao, Yingchun, Li, Haodong, Sun, Lihua, Yu, Qi, Gong, Manyu, Liu, Dongping, Wang, Yanying, Xuan, Lina, Yang, Xuewen, Qu, Yunmeng, Wang, Yaqi, Jiang, Lintong, Han, Jingjing, Zhang, Ying, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617129/
https://www.ncbi.nlm.nih.gov/pubmed/36317130
http://dx.doi.org/10.1016/j.jacbts.2022.06.004