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Protocol to identify functional doppelgängers and verify biomedical gene expression data using doppelgangerIdentifier

Functional doppelgängers (FDs) are independently derived sample pairs that confound machine learning model (ML) performance when assorted across training and validation sets. Here, we detail the use of doppelgangerIdentifier (DI), providing software installation, data preparation, doppelgänger ident...

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Detalles Bibliográficos
Autores principales: Wang, Li Rong, Fan, Xiuyi, Goh, Wilson Wen Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617193/
https://www.ncbi.nlm.nih.gov/pubmed/36317174
http://dx.doi.org/10.1016/j.xpro.2022.101783