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Protocol to identify functional doppelgängers and verify biomedical gene expression data using doppelgangerIdentifier
Functional doppelgängers (FDs) are independently derived sample pairs that confound machine learning model (ML) performance when assorted across training and validation sets. Here, we detail the use of doppelgangerIdentifier (DI), providing software installation, data preparation, doppelgänger ident...
Autores principales: | Wang, Li Rong, Fan, Xiuyi, Goh, Wilson Wen Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617193/ https://www.ncbi.nlm.nih.gov/pubmed/36317174 http://dx.doi.org/10.1016/j.xpro.2022.101783 |
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