High-content live-cell multiplex screen for chemogenomic compound annotation based on nuclear morphology

Well-characterized small molecules enable the study of cell processes and facilitate target validation. Here, we describe a high-content multiplex screen to investigate cell viability over 48 h, which can be combined with investigating phenotypic features, such as tubulin binding and mitochondrial c...

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Detalles Bibliográficos
Autores principales: Tjaden, Amelie, Giessmann, Robert T., Knapp, Stefan, Schröder, Martin, Müller, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617200/
https://www.ncbi.nlm.nih.gov/pubmed/36317177
http://dx.doi.org/10.1016/j.xpro.2022.101791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617200/
https://www.ncbi.nlm.nih.gov/pubmed/36317177
http://dx.doi.org/10.1016/j.xpro.2022.101791

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