Cargando…
High-content live-cell multiplex screen for chemogenomic compound annotation based on nuclear morphology
Well-characterized small molecules enable the study of cell processes and facilitate target validation. Here, we describe a high-content multiplex screen to investigate cell viability over 48 h, which can be combined with investigating phenotypic features, such as tubulin binding and mitochondrial c...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617200/ https://www.ncbi.nlm.nih.gov/pubmed/36317177 http://dx.doi.org/10.1016/j.xpro.2022.101791 |