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Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications
Anti-melanoma differentiation-associated gene 5-positive dermatomyositis (MDA5(+) DM) is an autoimmune condition associated with rapidly progressive interstitial lung disease and high mortality. The aetiology and pathogenesis of MDA5(+) DM are still largely unknown. Here we describe the immune signa...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617246/ https://www.ncbi.nlm.nih.gov/pubmed/36309526 http://dx.doi.org/10.1038/s41467-022-34145-4 |