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Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications

Anti-melanoma differentiation-associated gene 5-positive dermatomyositis (MDA5(+) DM) is an autoimmune condition associated with rapidly progressive interstitial lung disease and high mortality. The aetiology and pathogenesis of MDA5(+) DM are still largely unknown. Here we describe the immune signa...

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Detalles Bibliográficos
Autores principales: Ye, Yan, Chen, Zechuan, Jiang, Shan, Jia, Fengyun, Li, Teng, Lu, Xia, Xue, Jing, Lian, Xinyue, Ma, Jiaqiang, Hao, Pei, Lu, Liangjing, Ye, Shuang, Shen, Nan, Bao, Chunde, Fu, Qiong, Zhang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617246/
https://www.ncbi.nlm.nih.gov/pubmed/36309526
http://dx.doi.org/10.1038/s41467-022-34145-4