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The role of plasminogen activator inhibitor-2 in pneumococcal meningitis

Pneumococcal meningitis is associated with dysregulation of the coagulation cascade. Previously, we detected upregulation of cerebral plasminogen activator inhibitor-2 (PAI-2) mRNA expression during pneumococcal meningitis. Diverse functions have been ascribed to PAI-2, but its role remains unclear....

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Detalles Bibliográficos
Autores principales: Teske, Nina C., Engelen-Lee, Joo-Yeon, Dyckhoff-Shen, Susanne, Pfister, Hans-Walter, Klein, Matthias, van de Beek, Diederik, Kirschning, Carsten K., Koedel, Uwe, Brouwer, Matthijs C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617400/
https://www.ncbi.nlm.nih.gov/pubmed/36309755
http://dx.doi.org/10.1186/s40478-022-01461-1